There are a variety of DNA polymerases in both bacterial and eukaryotic cells. Targeting which one of the following properties of DNA polymerases would result in inhibiting DNA synthesis?
选项：

A:The initiation de novo of the synthesis of new DNA strands
B:The formation of phosphodiester bonds through hydrogen bonding
C:The cleavage of released pyrophosphate that provides the energy for the polymerization reaction
D:The dissociation and reassociation of the enzyme with DNA as each nucleotide is added to an existing DNA chain
E: The process of copying a template strand in its 3′-to-5′ direction, producing a new strand in the 5′-to-3′ direction