(单选题,)nullA distance runner is training for her half marathon and as part of the training is allowing her muscles to use fatty acids as a fuel source. Fatty acids are converted to acetyl-CoA in the mitochondria, at which point the acetyl-CoA can be oxidized in the TCA cycle to generate reduced cofactors. Which one of the following correctly describes how the acetyl-CoA is metabolized in the mitochondria?
选项：

A: One molecule of acetyl-CoA produces two molecules of CO2, three molecules of NADH, one molecule of FAD(2H) and one molecule of ATP.
B: NAD+ is the only electron acceptor in the cycle.
C: The TCA cycle requires large amounts of vitamins C and D ascoenzymes.
D: All of the energy for high-energy phosphate bonds is derived from oxidative phosphorylation.
E: Substrate-level phosphorylation generates one high-energy phosphate bond during the cycle.